Removing recalcitrance as an economic barrier for sustainable cellulosic biofuels
Biomass recalcitrance is the primary barrier to efficiently and economically accessing fermentable sugars for advanced biofuels that will directly displace petroleum. Convinced that biotechnological approaches hold the most promise for achieving these breakthroughs, the BioEnergy Science Center (BESC) is developing plants that are easier to deconstruct and microbes that more effectively convert lignocellulose into simple sugars.
BESC research involves working with two potential bioenergy crops (switchgrass and Populus) to develop varieties that are easier to break down into fermentable sugars and to understand how plant cell walls are formed and can be modified to improve sugar release.
BESC research in biomass deconstruction and conversion targets consolidated bioprocessing (a single-step process) by studying model organisms and thermophilic anaerobes to understand novel strategies and enzyme complexes for biomass deconstruction.
BESC researchers in characterization, modeling, and data management areas are engaged in (1) applying advanced technologies to analyze chemical and structural changes within biomass, and (2) storing, tracking, analyzing, and integrating data and understanding across the center.
Identification of key transcription factor that controls chlorophyll degradation and leaf senescence
New Insights into Biomass Deconstruction from Deletion of Genes in Caldicellulosiruptor
Rapid gene discovery and validation using the BESC Populus association population
Characterization of various alkaline pretreatment methods on cellulose structure and accessibility (A joint BESC/ORNL Biofuels SFA effort)
BESC Novel Approach to Bioenergy Outreach and Education
Switchgrass transcription factors linked to nutrient efficiency in senescence
Toward improving tolerance of thermophilic microorganisms to pretreatment inhibitors
Field performance of modified switchgrass demonstrates a 'Goldilocks Effect'
High-Performance Computing Delineates Chemistry of Lignin Synthesis
Review paper summarizes insights from 20 years of bacterial genome sequencing
Release of a genome dataset comprised of results from multiple sequencing modalities
Overexpression of gibberellin 2-oxidases leads to reduced recalcitrance in switchgrass
ORNL TITAN supercomputer used to determine molecular basis of reduced recalcitrance
- view document] High-throughput method for determining the sugar contant in biomass with pyrolysis molecular beam mass spectrometry [
- view document] Sequence data for clostridium autoethanogenum using three generations of sequencing technologies [
- Identifying promoters for gene expression in clostridium thermocellum [document not available]
- view document] 3-way networks: application of hypergraphs for modelling increased complexity in comparative genomics [
- view document] Homologous expression of the Caldicellulosiruptor bescii CelA reveals that the extracellular protein is glycosylated [
- Nucleic Acid Molecules Conferring Enhanced Ethanol Tolerance and Microorganisms Having Enhanced Tolerance to Ethanol
- Superactive Cellulase for Biomass Conversion
- Grass Fungal Endophytes and Uses Thereof
- Genes to Increase Growth in Monocots
- Universal Gene Transfer Technology for Gram Positive Bacteria
This is a random selection of BESC's intellectual property available for licensing. See all 32.
- New ORNL N.C. State, LanzaTech DNA dataset is potent, accessible tool
- UGA Rsearchers create fast-growing trees that are easier to turn into fuel
- Unique Proteins Found in Heat-Loving Organisms Bind Well to Plant Matter
- Novel pretreatment could cut biofuel costs by 30 percent or more
- Dr. Wellington Muchero Sugar and Splice "Exploring poplar genes for biofuel production"
- Keep up with BESC on our blog